2YEO
A39L mutation of scorpion toxin lqh-alpha-it
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ALPHA-INSECT TOXIN LQHAIT | polymer | 65 | 7438.5 | 1 | UniProt (P17728) Pfam (PF00537) | LEIURUS QUINQUESTRIATUS HEBRAEUS (SCORPION) | MUTANT OF NEUROTOXIN ALPHA-IT, LQH-ALPHA-IT, ALPHA-IT |
| 2 | B (A) | N,N,N-TRIMETHYLHEPTA-1,3,5-TRIYN-1-AMINIUM | non-polymer | 146.2 | 1 | Chemie (DR8) | |||
| 3 | C (A) | N-(HYDROXYMETHYL)-N,N-DIMETHYLHEXAN-1-AMINIUM | non-polymer | 160.3 | 1 | Chemie (DR0) | |||
| 4 | D, E, H, J (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | F, G, I (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 6 | K (A) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A: 2 - 65 (UniProt: P17728)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Leu 40 | Ala 58 | engineered mutation |
| Arg 65 | His 83 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 7438.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 661.1 | |
| All* | Total formula weight | 8099.7 |
