2YEO

A39L mutation of scorpion toxin lqh-alpha-it

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0006952	biological_process	defense response
A	0008200	molecular_function	ion channel inhibitor activity
A	0017080	molecular_function	sodium channel regulator activity
A	0019871	molecular_function	sodium channel inhibitor activity
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity
A	0099106	molecular_function	ion channel regulator activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE DR8 A 1066

Chain	Residue
A	TYR36
A	TYR36
A	TYR36
A	TYR50
A	TYR50
A	TYR50

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE DR0 A 1067

Chain	Residue
A	TRP39
A	CL1071
A	EDO1074
A	HOH2071
A	ASP20
A	TYR36
A	CYS37

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 1068

Chain	Residue
A	ASP20
A	ASN24
A	GLY35
A	TYR36
A	TYR36
A	TRP48
A	EDO1069
A	HOH2084

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 1069

Chain	Residue
A	TYR6
A	ASP20
A	ALA21
A	ASN24
A	EDO1068
A	HOH2057
A	HOH2104

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 1070

Chain	Residue
A	VAL14
A	ARG59
A	CYS64

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 1071

Chain	Residue
A	TRP39
A	DR01067
A	HOH2071

---

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 1072

Chain	Residue
A	ILE7
A	ALA8
A	LYS9
A	TYR15
A	ASN30
A	VAL56
A	HOH2105
A	HOH2106

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 1073

Chain	Residue
A	ARG19
A	HOH2051

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site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 1074

Chain	Residue
A	PHE18
A	ARG19
A	TRP39
A	LEU40
A	DR01067
A	HOH2107
A	HOH2108

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