2YDX
Crystal structure of human S-adenosylmethionine synthetase 2, beta subunit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA | polymer | 315 | 35546.4 | 5 | UniProt (Q9NZL9) Pfam (PF04321) | HOMO SAPIENS (HUMAN) | DTDP-4-KETO-6-DEOXY-D-GLUCOSE 4-REDUCTASE, METHIONINE ADENOSYLTRANSFERASE II BETA, MAT II BETA, S-ADENOSYLMETHIONINE SYNTHETASE 2, MAT2B |
| 2 | BA, CA, F, G, HA... (D, A, E, B, C) | RESVERATROL | non-polymer | 228.2 | 10 | Chemie (STL) PubChem (5056) PubChem (445154) PubChem (1548910) | |||
| 3 | DA, H, P, X (D, A, B, C) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (71717786) PubChem (165382010) | |||
| 4 | AA, EA, FA, GA, I... (C, D, A, E, B) | SULFATE ION | non-polymer | 96.1 | 19 | Chemie (SO4) | |||
| 5 | M (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) | |||
| 6 | JA (E) | 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE | non-polymer | 747.4 | 1 | Chemie (TXP) PubChem (444643) PubChem (89061866) PubChem (138753358) PubChem (166593727) | |||
| 7 | OA, PA, QA, RA, SA (A, B, C, D, E) | water | water | 18.0 | 523 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 28 - 334 (UniProt: Q9NZL9)
| PDB | External Database | Details |
|---|---|---|
| Met 27 | - | expression tag |
| Ala 335 | - | expression tag |
| Glu 336 | - | expression tag |
| Asn 337 | - | expression tag |
| Leu 338 | - | expression tag |
| Tyr 339 | - | expression tag |
| Phe 340 | - | expression tag |
| Gln 341 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 177731.9 | |
| Non-Polymers* | Number of molecules | 35 |
| Total formula weight | 7868.8 | |
| All* | Total formula weight | 185600.6 |
