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2YB9

Crystal Structure of Human Neutral Endopeptidase complexed with a heteroarylalanine diacid.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
NEPRILYSINpolymer69679525.51UniProt (P08473)
Pfam (PF05649)
Pfam (PF01431)
HOMO SAPIENS (HUMAN)NEUTRAL ENDOPEPTIDASE, ATRIOPEPTIDASE, COMMON ACUTE LYMPHOCYTIC LEUKEMIA ANTIGEN, CALLA, ENKEPHALINASE, NEUTRAL ENDOPEPTIDASE 24.11, NEP, NEUTRAL ENDOPEPTIDASE, SKIN FIBROBLAST ELASTASE, SFE, CD10
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
HETEROARYLALANINE 5-PHENYL OXAZOLEnon-polymer442.51Chemie (HA0)
4D
(A)
waterwater18.0482Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight79525.5
Non-Polymers*Number of molecules2
Total formula weight507.9
All*Total formula weight80033.4
*Water molecules are not included.

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PDB entries from 2025-11-12

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