2Y0I
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH TANKYRASE-2 (TNKS2) FRAGMENT PEPTIDE (21-MER)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR | polymer | 352 | 40610.6 | 1 | UniProt (Q9NWT6) Pfam (PF13621) | HOMO SAPIENS (HUMAN) | FACTOR INHIBITING HIF-1, FIH-1, HYPOXIA-INDUCIBLE FACTOR ASPARAGINE HYDROXYLASE |
| 2 | B (S) | TANKYRASE-2 | polymer | 21 | 2326.6 | 1 | UniProt (Q9H2K2) | HOMO SAPIENS | TANK2, POLY [ADP-RIBOSE] POLYMERASE 5B, TNKS-2, TRF1-INTERACTING ANKYRIN-RELATED ADP-RIBOSE POLYMERASE 2, TANKYRASE II, TANKYRASE-LIKE PROTEIN, TANKYRASE-RELATED PROTEIN |
| 3 | C (A) | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) | |||
| 4 | D (A) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) | |||
| 5 | E, F, G (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | H, I (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | J, K (A, S) | water | water | 18.0 | 114 | Chemie (HOH) |
Sequence modifications
A: 1 - 349 (UniProt: Q9NWT6)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42937.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 674.3 | |
| All* | Total formula weight | 43611.5 |
