2XWT
CRYSTAL STRUCTURE OF THE TSH RECEPTOR IN COMPLEX WITH A BLOCKING TYPE TSHR AUTOANTIBODY
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | THYROID BLOCKING HUMAN AUTOANTIBODY K1-70 HEAVY CHAIN | polymer | 221 | 23637.6 | 1 | HOMO SAPIENS (HUMAN) | ||
| 2 | B (B) | THYROID BLOCKING HUMAN AUTOANTIBODY K1-70 LIGHT CHAIN | polymer | 214 | 22598.1 | 1 | HOMO SAPIENS (HUMAN) | ||
| 3 | C (C) | THYROTROPIN RECEPTOR | polymer | 239 | 26943.8 | 1 | UniProt (P16473) Pfam (PF13306) | HOMO SAPIENS (HUMAN) | THYROID-STIMULATING HORMONE RECEPTOR, TSH-R |
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E (E) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 6 | F, G (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 7 | H, I, J (A, B, C) | water | water | 18.0 | 798 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 73179.5 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1173.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 74795.0 |
