2XWT

CRYSTAL STRUCTURE OF THE TSH RECEPTOR IN COMPLEX WITH A BLOCKING TYPE TSHR AUTOANTIBODY

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0004996	molecular_function	thyroid-stimulating hormone receptor activity
C	0007186	biological_process	G protein-coupled receptor signaling pathway
C	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCRVTH

Chain	Residue	Details
B	TYR192-HIS198
A	TYR206-HIS212

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:11502179, ECO:0000269|PubMed:17542669

Chain	Residue	Details
C	ASN77
C	ASN113
C	ASN198

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17542669

Chain	Residue	Details
C	ASN99
C	ASN177

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