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2XT3

HUMAN KIF7, A KINESIN INVOLVED IN HEDGEHOG SIGNALLING

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
KINESIN-LIKE PROTEIN KIF7polymer34437422.41UniProt (Q2M1P5)
Pfam (PF00225)
HOMO SAPIENS (HUMAN)KINESIN
2B
(A)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D
(A)
waterwater18.0290Chemie (HOH)
Sequence modifications
A: 4 - 344 (UniProt: Q2M1P5)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ala 2-expression tag
Met 3-expression tag
Lys 223Glu 226engineered mutation
Leu 265Arg 268engineered mutation
Arg 266Leu 269engineered mutation
Asn 295His 298engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37422.4
Non-Polymers*Number of molecules2
Total formula weight451.5
All*Total formula weight37873.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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