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2XT3

HUMAN KIF7, A KINESIN INVOLVED IN HEDGEHOG SIGNALLING

Functional Information from GO Data
ChainGOidnamespacecontents
A0003777molecular_functionmicrotubule motor activity
A0005524molecular_functionATP binding
A0007018biological_processmicrotubule-based movement
A0008017molecular_functionmicrotubule binding
Functional Information from PDB Data
site_idAC1
Number of Residues20
DetailsBINDING SITE FOR RESIDUE ADP A 1345
ChainResidue
AARG18
ATHR98
ATYR99
AMG1346
AHOH2283
AHOH2284
AHOH2285
AHOH2286
AHOH2287
AHOH2288
AHOH2289
APRO21
AHOH2290
ALEU23
AGLN92
ATHR93
AGLY94
ASER95
AGLY96
ALYS97

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG A 1346
ChainResidue
ATHR98
AADP1345
AHOH2104
AHOH2213
AHOH2284
AHOH2285

Functional Information from PROSITE/UniProt
site_idPS00411
Number of Residues12
DetailsKINESIN_MOTOR_1 Kinesin motor domain signature. SKFhFVDLAGSE
ChainResidueDetails
ASER243-GLU254

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00283
ChainResidueDetails
AGLY91

226707

PDB entries from 2024-10-30

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