2XMN
High resolution snapshots of defined TolC open states present an iris- like movement of periplasmic entrance helices
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Outer membrane protein TolC | polymer | 428 | 46917.7 | 3 | UniProt (P02930) Pfam (PF02321) In PDB | Escherichia coli (strain K12) | Multidrug efflux pump subunit TolC,Outer membrane factor TolC |
| 2 | A, B, C | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 3 | B | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 1 | Chemie (LMT) | |||
| 4 | water | water | 18.0 | 20 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 428 (UniProt: P02930)
| PDB | External Database | Details |
|---|---|---|
| Leu 169 | Val 191 | conflict |
| Phe 362 | Tyr 384 | engineered mutation |
| Ser 367 | Arg 389 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 140753.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 617.0 | |
| All* | Total formula weight | 141370.1 |
