2XF0
Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | SERINE/THREONINE-PROTEIN KINASE CHK1 | polymer | 289 | 33043.0 | 1 | UniProt (O14757) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | CHECKPOINT KINASE 1, CHEK1, CHK1 |
| 2 | A | 3-PHENYL-6-(1H-PYRAZOL-4-YL)IMIDAZO[1,2-A]PYRAZINE | non-polymer | 261.3 | 1 | Chemie (4UB) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33043.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 509.6 | |
| All* | Total formula weight | 33552.5 |
