2XE4

Structure of Oligopeptidase B from Leishmania major

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	OLIGOPEPTIDASE B	polymer	751	85244.3	1	UniProt (Q4QHU7) Pfam (PF02897) Pfam (PF00326)	LEISHMANIA MAJOR	FAMILY S9A-LIKE PROTEIN, SERINE PEPTIDASE
2	B (B)	ANTIPAIN	polymer	4	606.7	1	NOR (NOR00664) BIRD (PRD_002097)	ACTINOBACTERIA
3	C, D, E, F, G... (A)	GLYCEROL	non-polymer		92.1	10	Chemie (GOL)
4	AA, AB, BA, BB, CA... (A)	R-1,2-PROPANEDIOL	non-polymer		76.1	48	Chemie (PGR)
5	N (A)	S-1,2-PROPANEDIOL	non-polymer		76.1	1	Chemie (PGO)
6	JB, KB, LB (A)	PHOSPHATE ION	non-polymer		95.0	3	Chemie (PO4)
7	MB, OB, QB, RB (A)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
8	NB, PB (A)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
9	SB (A)	water	water		18.0	721	Chemie (HOH)

Sequence modifications

A: 1 - 731 (UniProt: Q4QHU7)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Leu 25	Phe 25	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	85851.0
Non-Polymers*	Number of molecules	68
	Total formula weight	5122.3
All*	Total formula weight	90973.3

*Water molecules are not included.