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2X7K

The crystal structure of PPIL1 in complex with cyclosporine A suggests a binding mode for SKIP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 1polymer16618257.81UniProt (Q9Y3C6)
Pfam (PF00160)
HOMO SAPIENS (HUMAN)PPIASE, ROTAMASE, PPIL1
2B
(B)
CYCLOSPORIN Apolymer111220.61NOR (NOR00033)
BIRD (PRD_000142)
TOLYPOCLADIUM INFLATUMCICLOSPORIN, CICLOSPORINE
3C, D
(A)
CADMIUM IONnon-polymer112.42Chemie (CD)
4E
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
5F, G
(A, B)
waterwater18.0294Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight19478.4
Non-Polymers*Number of molecules3
Total formula weight247.8
All*Total formula weight19726.2
*Water molecules are not included.

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PDB entries from 2025-06-25

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