Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000398 | biological_process | mRNA splicing, via spliceosome |
A | 0000413 | biological_process | protein peptidyl-prolyl isomerization |
A | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005634 | cellular_component | nucleus |
A | 0005654 | cellular_component | nucleoplasm |
A | 0005681 | cellular_component | spliceosomal complex |
A | 0006397 | biological_process | mRNA processing |
A | 0006457 | biological_process | protein folding |
A | 0008380 | biological_process | RNA splicing |
A | 0016018 | molecular_function | cyclosporin A binding |
A | 0016853 | molecular_function | isomerase activity |
A | 0071007 | cellular_component | U2-type catalytic step 2 spliceosome |
A | 0071013 | cellular_component | catalytic step 2 spliceosome |
A | 0097718 | molecular_function | disordered domain specific binding |
A | 1990403 | biological_process | embryonic brain development |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CD A 1167 |
Chain | Residue |
A | HIS31 |
A | ASP89 |
A | CYS133 |
A | HOH2087 |
A | HOH2190 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CD A 1168 |
Chain | Residue |
A | GLU26 |
A | HIS87 |
A | CYS133 |
A | HOH2239 |
site_id | AC3 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE NA A 1169 |
Chain | Residue |
A | ASP7 |
A | HOH2267 |
site_id | AC4 |
Number of Residues | 25 |
Details | BINDING SITE FOR CHAIN B OF CYCLOSPORIN A |
Chain | Residue |
A | GLU17 |
A | ARG55 |
A | PHE60 |
A | GLN63 |
A | GLY71 |
A | ALA101 |
A | ASN102 |
A | GLN111 |
A | PHE113 |
A | TRP121 |
A | HIS126 |
A | MET144 |
A | HOH2032 |
A | HOH2033 |
A | HOH2066 |
A | HOH2137 |
A | HOH2161 |
B | HOH2001 |
B | HOH2002 |
B | HOH2003 |
B | HOH2004 |
B | HOH2005 |
B | HOH2006 |
B | HOH2007 |
B | HOH2008 |
Functional Information from PROSITE/UniProt
site_id | PS00170 |
Number of Residues | 18 |
Details | CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YngTkFHRIIkdFMiQGG |
Chain | Residue | Details |
A | TYR48-GLY65 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | HIS54 | |
A | THR70 | |
A | ALA99 | |
A | GLY109 | |
A | THR119 | |
A | LYS125 | |
Chain | Residue | Details |
A | SER149 | |