2X7D
Crystal structure of human kinesin Eg5 in complex with (S)-dimethylenastron
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | KINESIN-LIKE PROTEIN KIF11 | polymer | 368 | 41055.6 | 2 | UniProt (P52732) Pfam (PF00225) | HOMO SAPIENS (HUMAN) | KINESIN-RELATED MOTOR PROTEIN EG5, KINESIN-LIKE SPINDLE PROTEIN HKSP, THYROID RECEPTOR-INTERACTING PROTEIN 5, EG5, TRIP-5, KINESIN-LIKE PROTEIN 1 |
| 2 | C, G (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 3 | D, E, H, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | F, J (A, B) | (4S)-4-(3-HYDROXYPHENYL)-7,7-DIMETHYL-2-THIOXO-2,3,4,6,7,8-HEXAHYDROQUINAZOLIN-5(1H)-ONE | non-polymer | 302.4 | 2 | Chemie (EGB) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 531 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82111.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1556.4 | |
| All* | Total formula weight | 83667.6 |
