2X63
Crystal structure of the sialyltransferase CST-II N51A in complex with CMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ALPHA-2,3-/2,8-SIALYLTRANSFERASE | polymer | 258 | 30343.4 | 1 | UniProt (Q9LAK3) Pfam (PF06002) | CAMPYLOBACTER JEJUNI | ALPHA-2\,3/8-SIALYLTRANSFERASE, SIALYLTRANSFERASE CST-II |
| 2 | B (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 3 | C (A) | CYTIDINE-5'-MONOPHOSPHATE | non-polymer | 323.2 | 1 | Chemie (C5P) | |||
| 4 | D (A) | water | water | 18.0 | 176 | Chemie (HOH) |
Sequence modifications
A: 2 - 259 (UniProt: Q9LAK3)
| PDB | External Database | Details |
|---|---|---|
| Ala 51 | Asn 51 | engineered mutation |
| Ser 53 | Ile 53 | engineered mutation |
| Gly 222 | Glu 222 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30343.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 385.3 | |
| All* | Total formula weight | 30728.7 |
