2X63
Crystal structure of the sialyltransferase CST-II N51A in complex with CMP
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1260 |
| Chain | Residue |
| A | SER12 |
| A | GLU15 |
| A | CYS212 |
| A | PRO213 |
| A | ASN214 |
| A | SER215 |
| A | HOH2122 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE C5P A 1261 |
| Chain | Residue |
| A | GLY10 |
| A | PRO11 |
| A | CYS30 |
| A | ASN31 |
| A | THR131 |
| A | SER132 |
| A | GLY133 |
| A | GLY152 |
| A | ILE153 |
| A | ASP154 |
| A | PHE155 |
| A | TYR156 |
| A | SER160 |
| A | SER161 |
| A | TYR162 |
| A | HOH2004 |
| A | HOH2125 |
| A | HOH2140 |
| A | HOH2174 |
| A | HOH2175 |
| A | HOH2176 |
| A | GLY8 |
| A | ASN9 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 840 |
| Chain | Residue | Details |
| A | ARG129 | electrostatic stabiliser |
| A | TYR156 | electrostatic stabiliser |
| A | TYR162 | electrostatic stabiliser |
| A | HIS188 | activator, proton acceptor, proton donor |
