2X44

Structure of a strand-swapped dimeric form of CTLA-4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (D)	CYTOTOXIC T-LYMPHOCYTE PROTEIN 4	polymer	131	14092.1	1	UniProt (P16410) Pfam (PF07686)	HOMO SAPIENS (HUMAN)	CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED ANTIGEN 4, CTLA-4, CD152, CYTOTOXIC T-LYMPHOCYTE ANTIGEN 4
2	B (D)	water	water		18.0	50	Chemie (HOH)

Sequence modifications

D: 0 - 0 (PDB: 2X44)
D: 127 - 130 (PDB: 2X44)
D: 1 - 126 (UniProt: P16410)

PDB	External Database	Details
Ser 122	Cys 157	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	14092.1
All*	Total formula weight	14092.1

*Water molecules are not included.