2X38

The crystal structure of the murine class IA PI 3-kinase p110delta in complex with IC87114.

Replaces:  2WXE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM	polymer	940	107823.7	1	UniProt (Q3UDT3) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) UniProt (by SIFTS) (O35904) In PDB	MUS MUSCULUS (MOUSE)	PI3-KINASE P110 SUBUNIT DELTA, PTDINS-3-KINASE P110, P110DELTA, PI3K
2	A	2-[(6-AMINO-9H-PURIN-9-YL)METHYL]-5-METHYL-3-(2-METHYLPHENYL)QUINAZOLIN-4(3H)-ONE	non-polymer		397.4	1	Chemie (IC8)
3		water	water		18.0	40	Chemie (HOH)

Sequence modifications

A: 105 - 105 (PDB: 2X38)
A: 106 - 1044 (UniProt: Q3UDT3)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	107823.7
Non-Polymers*	Number of molecules	1
	Total formula weight	397.4
All*	Total formula weight	108221.1

*Water molecules are not included.