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2X2U

First two Cadherin-like domains from Human RET

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RETpolymer24628698.51UniProt (P07949)
Pfam (PF17756)
Pfam (PF00028)
HOMO SAPIENS (HUMAN)C-RET, RET, CADHERIN FAMILY MEMBER 12
2B
(B)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
3C, D, E, F, G...
(A)
UNKNOWN ATOM OR IONnon-polymer11Chemie (UNX)
4N, O, P, Q, R...
(A)
SULFATE IONnon-polymer96.18Chemie (SO4)
5V, W
(A)
1,4-BUTANEDIOLnon-polymer90.12Chemie (BU1)
6X
(A)
waterwater18.0216Chemie (HOH)
Sequence modifications
A: 29 - 270 (UniProt: P07949)
PDBExternal DatabaseDetails
Arg 87Cys 87engineered mutation
Gln 98Asn 98engineered mutation
Gln 199Asn 199engineered mutation
Ser 216Cys 216engineered mutation
Glu 271-expression tag
Phe 272-expression tag
Glu 273-expression tag
Asn 274-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28698.5
BranchedNumber of molecules1
Total formula weight424.4
Non-Polymers*Number of molecules21
Total formula weight948.7
All*Total formula weight30071.6
*Water molecules are not included.

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PDB entries from 2025-07-30

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