2X2K
Crystal Structure of phosphorylated RET tyrosine kinase domain with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET | polymer | 314 | 35788.2 | 1 | UniProt (P07949) Pfam (PF07714) | HOMO SAPIENS (HUMAN) | C-RET |
| 2 | B, C, D (A) | FORMIC ACID | non-polymer | 46.0 | 3 | Chemie (FMT) | |||
| 3 | E (A) | (3Z)-5-amino-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one | non-polymer | 253.3 | 1 | Chemie (X2K) | |||
| 4 | F (A) | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35788.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 391.4 | |
| All* | Total formula weight | 36179.6 |
