2X2K
Crystal Structure of phosphorylated RET tyrosine kinase domain with inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET | polymer | 314 | 35788.2 | 1 | UniProt (P07949) Pfam (PF07714) In PDB | HOMO SAPIENS (HUMAN) | C-RET |
2 | A | FORMIC ACID | non-polymer | 46.0 | 3 | Chemie (FMT) | |||
3 | A | (3Z)-5-amino-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one | non-polymer | 253.3 | 1 | Chemie (X2K) | |||
4 | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35788.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 391.4 | |
All* | Total formula weight | 36179.6 |