2WV2
X-ray structure of CYP51 from the human pathogen Trypanosoma brucei in complex with fluconazole
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | LANOSTEROL 14-ALPHA-DEMETHYLASE | polymer | 475 | 53975.6 | 1 | UniProt (Q385E8) Pfam (PF00067) In PDB | TRYPANOSOMA BRUCEI | STEROL 14 ALPHA-DEMETHYLASE, CYP51 |
2 | A | 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL | non-polymer | 306.3 | 1 | Chemie (TPF) | |||
3 | A | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
4 | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 53975.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 922.8 | |
All* | Total formula weight | 54898.4 |