Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0005635 | cellular_component | nuclear envelope |
A | 0005783 | cellular_component | endoplasmic reticulum |
A | 0008398 | molecular_function | sterol 14-demethylase activity |
A | 0016125 | biological_process | sterol metabolic process |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0044091 | biological_process | membrane biogenesis |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE TPF A 1 |
Chain | Residue |
A | TYR103 |
A | MET106 |
A | PHE110 |
A | TYR116 |
A | ALA291 |
A | LEU356 |
A | HEM1450 |
site_id | AC2 |
Number of Residues | 21 |
Details | BINDING SITE FOR RESIDUE HEM A 1450 |
Chain | Residue |
A | TYR116 |
A | ARG124 |
A | LEU127 |
A | LEU134 |
A | GLY292 |
A | THR295 |
A | THR299 |
A | LEU356 |
A | LEU359 |
A | ARG361 |
A | GLY414 |
A | PHE415 |
A | GLY416 |
A | VAL419 |
A | HIS420 |
A | CYS422 |
A | ILE423 |
A | GLY424 |
A | HOH2011 |
A | TPF1 |
A | TYR103 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGaGVHKCIG |
Chain | Residue | Details |
A | PHE415-GLY424 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1akd |
Chain | Residue | Details |
A | HIS294 | |
A | THR295 | |