2WUB
Crystal structure of HGFA in complex with the allosteric non- inhibitory antibody Fab40.deltaTrp
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | HEPATOCYTE GROWTH FACTOR ACTIVATOR LONG CHAIN | polymer | 257 | 27982.6 | 2 | UniProt (Q04756) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | |
| 2 | B, D (B, D) | HEPATOCYTE GROWTH FACTOR ACTIVATOR SHORT CHAIN | polymer | 35 | 3962.7 | 2 | UniProt (Q04756) | HOMO SAPIENS (HUMAN) | |
| 3 | E, H (H, R) | FAB FRAGMENT FAB40.DELTATRP HEAVY CHAIN | polymer | 224 | 23584.4 | 2 | HOMO SAPIENS (HUMAN) | ||
| 4 | F, G (L, Q) | FAB FRAGMENT FAB40.DELTATRP LIGHT CHAIN | polymer | 214 | 23238.7 | 2 | HOMO SAPIENS (HUMAN) | ||
| 5 | I, J (E, F) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 6 | K, L, M, N, O... (A, B, C, D, H...) | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 157536.9 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1173.1 | |
| All* | Total formula weight | 158709.9 |
