2WTF
DNA polymerase eta in complex with the cis-diammineplatinum (II) 1,3- GTG intrastrand cross-link
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | DNA POLYMERASE ETA | polymer | 536 | 60708.6 | 2 | UniProt (Q04049) Pfam (PF00817) Pfam (PF11799) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | DNA POLYMERASE ETA RAD30, RADIATION-SENSITIVE PROTEIN 30 |
2 | C, E (O, S) | 5'-D(*TP*CP*TP*TP*CP*TP*GP*TP*GP*CP *TP*CP*AP*CP*CP*AP*CP)-3' | polymer | 17 | 5089.3 | 2 | |||
3 | D, F (P, T) | 5'-D(*GP*TP*GP*GP*TP*GP*AP*GP*CP)-3' | polymer | 9 | 2811.8 | 2 | |||
4 | G, N (A, B) | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 2 | Chemie (DTP) | |||
5 | H, I, J, K, L... (A, B) | CALCIUM ION | non-polymer | 40.1 | 10 | Chemie (CA) | |||
6 | S, T (O, S) | Cisplatin | non-polymer | 300.0 | 2 | Chemie (CPT) | |||
7 | U, V, W (A, B, O) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 137219.6 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 1983.2 | |
All* | Total formula weight | 139202.8 |