2WO6

Human Dual-Specificity Tyrosine-Phosphorylation-Regulated Kinase 1A in complex with a consensus substrate peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION- REGULATED KINASE 1A	polymer	382	44553.2	2	UniProt (Q13627) Pfam (PF00069) In PDB	HOMO SAPIENS (HUMAN)	PROTEIN KINASE MINIBRAIN HOMOLOG, HP86, DUAL SPECIFICITY YAK1-RELATED KINASE, MNBH, HMNB
2	C	ARTIFICIAL CONSENSUS SEQUENCE	polymer	8	782.9	1	UniProt (by SIFTS) (Q5IJ48) In PDB	SYNTHETIC CONSTRUCT
3	A, B	N-(5-{[(2S)-4-amino-2-(3-chlorophenyl)butanoyl]amino}-1H-indazol-3-yl)benzamide	non-polymer		447.9	2	Chemie (D15)
4	B	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
5		water	water		18.0	272	Chemie (HOH)

Sequence modifications

A, B: 104 - 126 (PDB: 2WO6)
A, B: 127 - 485 (UniProt: Q13627)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	89889.3
Non-Polymers*	Number of molecules	3
	Total formula weight	931.3
All*	Total formula weight	90820.6

*Water molecules are not included.