2WO6
Human Dual-Specificity Tyrosine-Phosphorylation-Regulated Kinase 1A in complex with a consensus substrate peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION- REGULATED KINASE 1A | polymer | 382 | 44553.2 | 2 | UniProt (Q13627) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | PROTEIN KINASE MINIBRAIN HOMOLOG, HP86, DUAL SPECIFICITY YAK1-RELATED KINASE, MNBH, HMNB |
| 2 | C (C) | ARTIFICIAL CONSENSUS SEQUENCE | polymer | 8 | 782.9 | 1 | UniProt (by SIFTS) (Q5IJ48) | SYNTHETIC CONSTRUCT | |
| 3 | D, E (A, B) | N-(5-{[(2S)-4-amino-2-(3-chlorophenyl)butanoyl]amino}-1H-indazol-3-yl)benzamide | non-polymer | 447.9 | 2 | Chemie (D15) | |||
| 4 | F (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 89889.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 931.3 | |
| All* | Total formula weight | 90820.6 |
