2WNS

Human Orotate phosphoribosyltransferase (OPRTase) domain of Uridine 5' -monophosphate synthase (UMPS) in complex with its substrate orotidine 5'-monophosphate (OMP)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	OROTATE PHOSPHORIBOSYLTRANSFERASE	polymer	205	22615.2	2	UniProt (P11172) Pfam (PF00156)	HOMO SAPIENS (HUMAN)	OPRTASE, URIDINE 5'-MONOPHOSPHATE SYNTHASE
2	C, D (A, B)	OROTIDINE-5'-MONOPHOSPHATE	non-polymer		368.2	2	Chemie (OMP)
3	E (B)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	F, G (A, B)	water	water		18.0	237	Chemie (HOH)

Sequence modifications

A, B: 6 - 6 (PDB: 2WNS)
A, B: 204 - 210 (PDB: 2WNS)
A, B: 7 - 203 (UniProt: P11172)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45230.4
Non-Polymers*	Number of molecules	3
	Total formula weight	771.8
All*	Total formula weight	46002.2

*Water molecules are not included.