2WG3

Crystal structure of the complex between human hedgehog-interacting protein HIP and desert hedgehog without calcium

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DESERT HEDGEHOG PROTEIN N-PRODUCT	polymer	164	18662.8	2	UniProt (O43323) Pfam (PF01085)	HOMO SAPIENS (HUMAN)	DESERT HEDGEHOG PROTEIN, DHH, HHG-3
2	C, D (C, D)	HEDGEHOG-INTERACTING PROTEIN	polymer	463	51800.7	2	UniProt (Q96QV1) Pfam (PF07995) Pfam (PF07974)	HOMO SAPIENS (HUMAN)	HHIP, HIP, HEDGEHOG-INTERACTING PROTEIN HIP
3	E, G (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	F, J, K, N, O... (A, C, D)	CHLORIDE ION	non-polymer		35.5	6	Chemie (CL)
5	H, L (C, D)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
6	I, M (C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
7	Q, R, S, T (A, B, C, D)	water	water		18.0	123	Chemie (HOH)

Sequence modifications

A, B: 39 - 39 (PDB: 2WG3)
A, B: 195 - 202 (PDB: 2WG3)
A, B: 40 - 194 (UniProt: O43323)
C, D: 214 - 670 (UniProt: Q96QV1)
C, D: 671 - 676 (PDB: 2WG3)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	140927.1
Non-Polymers*	Number of molecules	12
	Total formula weight	975.9
All*	Total formula weight	141903.0

*Water molecules are not included.