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2WCO

Structures of the Streptomyces coelicolor A3(2) Hyaluronan Lyase in Complex with Oligosaccharide Substrates and an Inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
PUTATIVE SECRETED LYASEpolymer76583022.21UniProt (O86516)
Pfam (PF08124)
Pfam (PF02278)
Pfam (PF02884)
STREPTOMYCES COELICOLOR A3(2)POLYSACCHARIDE LYASE
2B
(B)
4-deoxy-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched381.31In PDB
GlyTouCan (G40515XE)
3C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4D, E
(A)
FORMIC ACIDnon-polymer46.02Chemie (FMT)
5F
(A)
waterwater18.0768Chemie (HOH)
Sequence modifications
A: 22 - 765 (UniProt: O86516)
PDBExternal DatabaseDetails
Met 1-expression tag
Gly 2-expression tag
Ser 3-expression tag
Ser 4-expression tag
His 5-expression tag
His 6-expression tag
His 7-expression tag
His 8-expression tag
His 9-expression tag
His 10-expression tag
Ser 11-expression tag
Ser 12-expression tag
Gly 13-expression tag
Leu 14-expression tag
Val 15-expression tag
Pro 16-expression tag
Arg 17-expression tag
Gly 18-expression tag
Ser 19-expression tag
His 20-expression tag
Met 21-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight83022.2
BranchedNumber of molecules1
Total formula weight381.3
Non-Polymers*Number of molecules3
Total formula weight184.1
All*Total formula weight83587.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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