2W5Z
Ternary Complex of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine and histone peptide.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HISTONE-LYSINE N-METHYLTRANSFERASE HRX | polymer | 192 | 22181.4 | 1 | UniProt (Q03164) Pfam (PF00856) | HOMO SAPIENS (HUMAN) | ZINC FINGER PROTEIN HRX, ALL-1, TRITHORAX-LIKE PROTEIN, LYSINE N-METHYLTRANSFERASE 2A, CXXC-TYPE ZINC FINGER PROTEIN 7, MLL-1 |
| 2 | B (C) | HISTONE PEPTIDE | polymer | 9 | 1124.3 | 1 | UniProt (by SIFTS) (P68433) | HOMO SAPIENS (HUMAN) | |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 5 | E, F (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | G, H (A, C) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 23305.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 634.0 | |
| All* | Total formula weight | 23939.7 |
