2W3W
MYCOBACTERIUM AVIUM DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND A LIPOPHILIC ANTIFOLATE SELECTIVE FOR M. AVIUM DHFR, 6-((2,5- DIETHOXYPHENYL)AMINOMETHYL)-2,4-DIAMINO-5-METHYLPYRIDO(2,3-D) PYRIMIDINE (SRI-8686)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DIHYDROFOLATE REDUCTASE | polymer | 167 | 18451.8 | 1 | UniProt (O30463) Pfam (PF00186) In PDB | MYCOBACTERIUM AVIUM | |
| 2 | A | 6-{[(2,5-DIETHOXYPHENYL)AMINO]METHYL}-5-METHYLPYRIDO[2,3-D]PYRIMIDINE-2,4-DIAMINE | non-polymer | 368.4 | 1 | Chemie (VG9) | |||
| 3 | A | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 4 | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18451.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1113.9 | |
| All* | Total formula weight | 19565.7 |
