2W2W

PLCg2 Split Pleckstrin Homology (PH) Domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2	polymer	124	14202.8	12	UniProt (P16885) In PDB	HOMO SAPIENS (HUMAN)	PHOSPHOINOSITIDE PHOSPHOLIPASE C, PHOSPHOLIPASE C-GAMMA-2, PLC-GAMMA-2, PLC-IV

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: -5 - 1 (PDB: 2W2W)
A, B, C, D, E, F, G, H, I, J, K, L: 2 - 46 (UniProt: P16885)

PDB	External Database	Details
Phe 26	Tyr 495	engineered mutation

A, B, C, D, E, F, G, H, I, J, K, L: 47 - 118 (UniProt: P16885)

PDB	External Database	Details
Asp 88	Tyr 883	conflict
Lys 97	Arg 892	conflict

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	170433.8
All*	Total formula weight	170433.8

*Water molecules are not included.