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2VWI

Structure of the OSR1 kinase, a hypertension drug target

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
SERINE/THREONINE-PROTEIN KINASE OSR1polymer30333997.34UniProt (O95747)
Pfam (PF00069)
HOMO SAPIENS (HUMAN)OXIDATIVE STRESS- RESPONSIVE 1 PROTEIN, OSR1
2E, G, H, J, L...
(A, B, C, D)
GOLD IONnon-polymer197.011Chemie (AU)
3F, K, P, T
(A, B, C, D)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.24Chemie (ANP)
4I, O, S
(B, C, D)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
5W, X, Y, Z
(A, B, C, D)
waterwater18.0228Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight135989.3
Non-Polymers*Number of molecules18
Total formula weight4264.3
All*Total formula weight140253.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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