2VUW
Structure of human haspin kinase domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE/THREONINE-PROTEIN KINASE HASPIN | polymer | 336 | 38615.0 | 1 | UniProt (Q8TF76) Pfam (PF12330) | HOMO SAPIENS (HUMAN) | HASPIN, HAPLOID GERM CELL-SPECIFIC NUCLEAR PROTEIN KINASE, H-HASPIN, GERM CELL-SPECIFIC GENE 2 PROTEIN |
| 2 | B (A) | IODIDE ION | non-polymer | 126.9 | 1 | Chemie (IOD) | |||
| 3 | C (A) | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL | non-polymer | 392.1 | 1 | Chemie (5ID) | |||
| 4 | D (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 5 | E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | F (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 7 | G (A) | water | water | 18.0 | 398 | Chemie (HOH) |
Sequence modifications
A: 465 - 798 (UniProt: Q8TF76)
| PDB | External Database | Details |
|---|---|---|
| Ser 463 | - | expression tag |
| Mse 464 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38615.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 774.1 | |
| All* | Total formula weight | 39389.0 |
