2VUW
Structure of human haspin kinase domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE/THREONINE-PROTEIN KINASE HASPIN | polymer | 336 | 38615.0 | 1 | UniProt (Q8TF76) Pfam (PF12330) | HOMO SAPIENS (HUMAN) | HASPIN, HAPLOID GERM CELL-SPECIFIC NUCLEAR PROTEIN KINASE, H-HASPIN, GERM CELL-SPECIFIC GENE 2 PROTEIN |
| 2 | B (A) | IODIDE ION | non-polymer | 126.9 | 1 | Chemie (IOD) PubChem (30165) | |||
| 3 | C (A) | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL | non-polymer | 392.1 | 1 | Chemie (5ID) PubChem (16760523) PubChem (1830) PubChem (97297) PubChem (23919584) PubChem (25880707) PubChem (26248662) PubChem (35028380) PubChem (46875276) PubChem (51386958) PubChem (51537014) PubChem (45039587) PubChem (59583554) PubChem (59583625) PubChem (6419781) PubChem (9886793) PubChem (14221929) PubChem (134695308) | |||
| 4 | D (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) PubChem (934) | |||
| 5 | E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) PubChem (679) | |||
| 6 | F (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 7 | G (A) | water | water | 18.0 | 398 | Chemie (HOH) |
Sequence modifications
A: 465 - 798 (UniProt: Q8TF76)
| PDB | External Database | Details |
|---|---|---|
| Ser 463 | - | expression tag |
| Mse 464 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38615.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 774.1 | |
| All* | Total formula weight | 39389.0 |
