2VQW
Structure of inhibitor-free HDAC4 catalytic domain (with gain-of- function mutation His332Tyr)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | G | HISTONE DEACETYLASE 4 | polymer | 413 | 44502.4 | 1 | UniProt (P56524) Pfam (PF00850) In PDB | HOMO SAPIENS (HUMAN) | HD4 |
| 2 | G | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 3 | G | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
G: 1 - 3 (PDB: 2VQW)
G: 4 - 413 (UniProt: P56524)
G: 4 - 413 (UniProt: P56524)
| PDB | External Database | Details |
|---|---|---|
| Tyr 332 | His 976 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44502.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 209.0 | |
| All* | Total formula weight | 44711.4 |
