2VQM

Structure of HDAC4 catalytic domain bound to a hydroxamic acid inhbitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	HISTONE DEACETYLASE 4	polymer	413	44477.4	1	UniProt (P56524) Pfam (PF00850) In PDB	HOMO SAPIENS (HUMAN)	HD4
2	A	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
3	A	N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide	non-polymer		368.4	1	Chemie (HA3)
4	A	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
5		water	water		18.0	360	Chemie (HOH)

Sequence modifications

A: 1 - 3 (PDB: 2VQM)
A: 4 - 413 (UniProt: P56524)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44477.4
Non-Polymers*	Number of molecules	5
	Total formula weight	577.4
All*	Total formula weight	45054.8

*Water molecules are not included.