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2VPP

Drosophila melanogaster deoxyribonucleoside kinase successfully activates gemcitabine in transduced cancer cell lines

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
DEOXYNUCLEOSIDE KINASEpolymer23026906.72UniProt (Q9XZT6)
Pfam (PF01712)
DROSOPHILA MELANOGASTER (FRUIT FLY)DEOXYRIBONUCLEOSIDE KINASE, DM-DNK, MULTISPECIFIC DEOXYNUCLEOSIDE KINASE
2C, E
(A, B)
GEMCITABINEnon-polymer263.22Chemie (GEO)
3D, F
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
4G, H
(A, B)
waterwater18.0239Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight53813.4
Non-Polymers*Number of molecules4
Total formula weight718.5
All*Total formula weight54531.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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