2VHS

Cathsilicatein, a chimera

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	CATHSILICATEIN	polymer	217	23719.4	4	UniProt (P07711) Pfam (PF00112)	HOMO SAPIENS (HUMAN)
2	E, F, G, H, I... (A, B, C, D)	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
3	M, N, O, P (A, B, C, D)	water	water		18.0	1172	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 172 (UniProt: P07711)

PDB	External Database	Details
Val 110	Thr 223	conflict
Ala 24	Ser 137	engineered mutation
Ser 25	Cys 138	engineered mutation
Tyr 26	Trp 139	engineered mutation
Ser 153	Glu 266	engineered mutation
Ser 154	Pro 267	engineered mutation
Ser 159	Glu 272	engineered mutation
Ser 160	Asp 273	engineered mutation
Leu 161	Met 274	engineered mutation
Asn 162	Asp 275	engineered mutation
Ala 164	Gly 277	engineered mutation
Met 165	Val 278	engineered mutation

A, B, C, D: 181 - 220 (UniProt: P07711)
A, B, C, D: 173 - 180 (PDB: 2VHS)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	94877.5
Non-Polymers*	Number of molecules	8
	Total formula weight	768.5
All*	Total formula weight	95646.0

*Water molecules are not included.