2VD7

Crystal Structure of JMJD2A complexed with inhibitor Pyridine-2,4- dicarboxylic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 3A	polymer	381	44326.3	2	UniProt (O75164) Pfam (PF02375) Pfam (PF02373) In PDB	HOMO SAPIENS (HUMAN)	JUMONJI DOMAIN-CONTAINING PROTEIN 2A
2	A, B	NICKEL (II) ION	non-polymer		58.7	2	Chemie (NI)
3	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	A, B	PYRIDINE-2,4-DICARBOXYLIC ACID	non-polymer		167.1	2	Chemie (PD2)
5		water	water		18.0	357	Chemie (HOH)

Sequence modifications

A, B: -21 - 0 (PDB: 2VD7)
A, B: 1 - 359 (UniProt: O75164)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	88652.5
Non-Polymers*	Number of molecules	6
	Total formula weight	582.4
All*	Total formula weight	89235.0

*Water molecules are not included.