2VD7
Crystal Structure of JMJD2A complexed with inhibitor Pyridine-2,4- dicarboxylic acid
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | SLS BEAMLINE X10SA |
Synchrotron site | SLS |
Beamline | X10SA |
Temperature [K] | 100 |
Detector technology | CCD |
Collection date | 2007-07-16 |
Detector | MARRESEARCH |
Spacegroup name | P 21 21 2 |
Unit cell lengths | 101.285, 149.121, 57.566 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 37.630 - 2.250 |
R-factor | 0.172 |
Rwork | 0.170 |
R-free | 0.21900 |
Structure solution method | MOLECULAR REPLACEMENT |
RMSD bond length | 0.014 |
RMSD bond angle | 1.439 |
Data reduction software | MOSFLM |
Data scaling software | SCALA |
Phasing software | REFMAC |
Refinement software | REFMAC (5.3.0040) |
Data quality characteristics
Overall | Outer shell | |
Low resolution limit [Å] | 38.010 | 2.370 |
High resolution limit [Å] | 2.250 | 2.250 |
Rmerge | 0.070 | 0.600 |
Number of reflections | 143382 | |
<I/σ(I)> | 12.2 | 2.5 |
Completeness [%] | 99.1 | 98.7 |
Redundancy | 3.5 | 3.2 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | 5.5 | 20% PEG3350 0.1M CITRATE PH 5.5 |