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2RK1

DHFR R67 Complexed with NADP and dihydrofolate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dihydrofolate reductase type 2polymer626732.51UniProt (P00383)
Pfam (PF06442)
Escherichia coliDihydrofolate reductase type II
2B
(A)
DIHYDROFOLIC ACIDnon-polymer443.41Chemie (DHF)
3C
(A)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
4D, E, F
(A)
(4R)-2-METHYLPENTANE-2,4-DIOLnon-polymer118.23Chemie (MRD)
5G
(A)
waterwater18.0109Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight6732.5
Non-Polymers*Number of molecules5
Total formula weight1541.3
All*Total formula weight8273.9
*Water molecules are not included.

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PDB entries from 2025-12-17

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