2RD0
Structure of a human p110alpha/p85alpha complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | polymer | 1096 | 127822.6 | 1 | UniProt (P42336) Pfam (PF02192) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) | Homo sapiens (human) | PI3-kinase p110 subunit alpha, PtdIns-3- kinase p110, PI3K |
| 2 | B (B) | Phosphatidylinositol 3-kinase regulatory subunit alpha | polymer | 279 | 33667.0 | 1 | UniProt (P27986) Pfam (PF00017) Pfam (PF16454) | Homo sapiens (human) | PI3-kinase p85 subunit alpha, PtdIns-3-kinase p85-alpha, PI3K |
Sequence modifications
A: 1 - 1068 (UniProt: P42336)
| PDB | External Database | Details |
|---|---|---|
| Met -28 | - | expression tag |
| Ser -27 | - | expression tag |
| Tyr -26 | - | expression tag |
| Tyr -25 | - | expression tag |
| His -24 | - | expression tag |
| His -23 | - | expression tag |
| His -22 | - | expression tag |
| His -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| Asp -18 | - | expression tag |
| Tyr -17 | - | expression tag |
| Asp -16 | - | expression tag |
| Ile -15 | - | expression tag |
| Pro -13 | - | expression tag |
| Thr -12 | - | expression tag |
| Thr -11 | - | expression tag |
| Glu -10 | - | expression tag |
| Asn -9 | - | expression tag |
| Leu -8 | - | expression tag |
| Tyr -7 | - | expression tag |
| Phe -6 | - | expression tag |
| Gln -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 161489.5 | |
| All* | Total formula weight | 161489.5 |
