2R7Z

Cisplatin lesion containing RNA polymerase II elongation complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	T	5'-D(*TP*AP*CP*TP*TP*GUP*CP*CP*CP*TP*CP*CP*TP*CP*AP*T)-3'	polymer	17	5089.3	1
2	N	5'-D(*CP*AP*AP*GP*TP*AP*G)-3'	polymer	7	2146.4	1
3	P	5'-R(*UP*UP*UP*GP*AP*GP*GP*AP*GP*G)-3'	polymer	10	3258.0	1
4	A	DNA-directed RNA polymerase II subunit RPB1	polymer	1733	191821.6	1	UniProt (P04050) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) In PDB	Saccharomyces cerevisiae (baker's yeast)	RNA polymerase II subunit B1; RNA polymerase II subunit 1; DNA-directed RNA polymerase III largest subunit; B220
5	B	DNA-directed RNA polymerase II subunit RPB2	polymer	1224	138937.3	1	UniProt (P08518) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) In PDB	Saccharomyces cerevisiae (baker's yeast)	RNA polymerase II subunit 2; DNA-directed RNA polymerase II 140 kDa polypeptide; B150
6	C	DNA-directed RNA polymerase II subunit RPB3	polymer	318	35330.5	1	UniProt (P16370) Pfam (PF01193) Pfam (PF01000) In PDB	Saccharomyces cerevisiae (baker's yeast)	RNA polymerase II subunit B3; RNA polymerase II subunit 3; DNA-directed RNA polymerase II 45 kDa polypeptide; B44.5
7	D	DNA-directed RNA polymerase II subunit RPB4	polymer	221	25451.2	1	UniProt (P20433) Pfam (PF03874) In PDB	Saccharomyces cerevisiae (baker's yeast)	RNA polymerase II subunit B4; DNA-directed RNA polymerase II 32 kDa polypeptide; B32
8	E	DNA-directed RNA polymerases I, II, and III subunit RPABC1	polymer	215	25117.1	1	UniProt (P20434) Pfam (PF03871) Pfam (PF01191) In PDB	Saccharomyces cerevisiae (baker's yeast)	'RNA
9	F	DNA-directed RNA polymerases I, II, and III subunit RPABC2	polymer	155	17931.8	1	UniProt (P20435) Pfam (PF01192) In PDB	Saccharomyces cerevisiae (baker's yeast)	RNA polymerases I, II, and III subunit ABC2; DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide; ABC23
10	G	DNA-directed RNA polymerase II subunit RPB7	polymer	171	19081.1	1	UniProt (P34087) Pfam (PF03876) Pfam (PF00575) In PDB	Saccharomyces cerevisiae (baker's yeast)	RNA polymerase II subunit B7; B16
11	H	DNA-directed RNA polymerases I, II, and III subunit RPABC3	polymer	146	16525.4	1	UniProt (P20436) Pfam (PF03870) In PDB	Saccharomyces cerevisiae (baker's yeast)	RNA polymerases I, II, and III subunit ABC3; DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide; ABC14.4; ABC14.5
12	I	DNA-directed RNA polymerase II subunit RPB9	polymer	122	14308.2	1	UniProt (P27999) Pfam (PF02150) Pfam (PF01096) In PDB	Saccharomyces cerevisiae (baker's yeast)	RNA polymerase II subunit B9; DNA-directed RNA polymerase II subunit 9; DNA-directed RNA polymerase II 14.2 kDa polypeptide; B12.6
13	J	DNA-directed RNA polymerases I, II, and III subunit RPABC5	polymer	70	8290.7	1	UniProt (P22139) Pfam (PF01194) In PDB	Saccharomyces cerevisiae (baker's yeast)	RNA polymerases I, II, and III subunit ABC5; DNA-directed RNA polymerases I, II, and III 8.3 kDa polypeptide; ABC10-beta; ABC8
14	K	DNA-directed RNA polymerase II subunit RPB11	polymer	120	13633.5	1	UniProt (P38902) Pfam (PF13656) In PDB	Saccharomyces cerevisiae (baker's yeast)	RNA polymerase II subunit B11; DNA-directed RNA polymerase II 13.6 kDa polypeptide; B13.6
15	L	DNA-directed RNA polymerases I, II, and III subunit RPABC4	polymer	70	7730.0	1	UniProt (P40422) Pfam (PF03604) In PDB	Saccharomyces cerevisiae (baker's yeast)	RNA polymerases I, II, and III subunit ABC4; ABC10-alpha
16	T	Cisplatin	non-polymer		300.0	1	Chemie (CPT)
17	A, B, C, I, J...	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
18	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)

Contents of the asymmetric unit

Polymers	Number of chains	15
	Total formula weight	524651.9
Non-Polymers*	Number of molecules	10
	Total formula weight	847.6
All*	Total formula weight	525499.6

*Water molecules are not included.