2R2M
2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thrombin light chain | polymer | 26 | 3075.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (Human) | |
| 2 | B (B) | Thrombin heavy chain | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | |
| 3 | C (H) | Hirudin-3A | polymer | 11 | 1411.5 | 1 | UniProt (P28507) UniProt (by SIFTS) (P09945) | Hirudo medicinalis (Medicinal leech) | Hirudin IIIA |
| 4 | D (B) | N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl}acetamide | non-polymer | 443.9 | 1 | Chemie (I50) | |||
| 5 | E, F, G (A, B, H) | water | water | 18.0 | 137 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 34267.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 443.9 | |
| All* | Total formula weight | 34711.0 |
