Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0007596 | biological_process | blood coagulation |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0006508 | biological_process | proteolysis |
| B | 0007596 | biological_process | blood coagulation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE I50 B 5000 |
| Chain | Residue |
| B | HIS79 |
| B | GLY258 |
| B | GLU259 |
| B | GLY260 |
| B | CYS261 |
| B | HOH5005 |
| B | HOH5099 |
| B | TYR83 |
| B | GLU130 |
| B | ASP229 |
| B | ALA230 |
| B | CYS231 |
| B | SER235 |
| B | SER256 |
| B | TRP257 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR CHAIN H OF HIRUDIN-3A |
| Chain | Residue |
| B | PHE55 |
| B | LYS57 |
| B | GLN60 |
| B | LEU62 |
| B | LEU96 |
| B | ARG104 |
| B | THR105 |
| B | ARG106 |
| B | TYR107 |
| B | MET116 |
| B | HOH5115 |
| B | HOH5122 |
| H | HOH301 |
| H | HOH302 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| B | LEU75-CYS80 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAceGDSGGPFV |
| Chain | Residue | Details |
| B | ASP229-VAL240 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| H | TYR298 | |
| B | ASP135 | |
| B | SER235 | |
| Chain | Residue | Details |
| B | ASN89 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | ASP135 | |
| B | HIS79 | |
| B | GLY233 | |
| B | SER235 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | ASP135 | |
| B | HIS79 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | GLY233 | |
| B | SER235 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | GLY236 | |
| B | SER235 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | ASP135 | |
| B | HIS79 | |
| B | SER235 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | GLY236 | |
| B | ASP135 | |
| B | HIS79 | |
| B | SER235 | |
