2QUI

Crystal structures of human tryptophanyl-tRNA synthetase in complex with Tryptophanamide and ATP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Tryptophanyl-tRNA synthetase	polymer	477	54060.1	2	UniProt (P23381) Pfam (PF00458) Pfam (PF00579) In PDB	Homo sapiens (human)	Tryptophan-tRNA ligase, TrpRS, Interferon-induced protein 53, IFP53, hWRS
2	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
3	A, B	L-TRYPTOPHANAMIDE	non-polymer		203.2	2	Chemie (LTN)
4	A	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)
5		water	water		18.0	226	Chemie (HOH)

Sequence modifications

A, B: 1 - 471 (UniProt: P23381)

PDB	External Database	Details
His 472	-	expression tag
His 473	-	expression tag
His 474	-	expression tag
His 475	-	expression tag
His 476	-	expression tag
His 477	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	108120.2
Non-Polymers*	Number of molecules	4
	Total formula weight	938.0
All*	Total formula weight	109058.2

*Water molecules are not included.