2QNA
Crystal structure of human Importin-beta (127-876) in complex with the IBB-domain of Snurportin1 (1-65)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Importin subunit beta-1 | polymer | 762 | 84567.4 | 1 | UniProt (Q14974) Pfam (PF00514) | Homo sapiens (human) | Karyopherin subunit beta-1, Nuclear factor P97, Importin 90 |
| 2 | B (B) | Snurportin-1 | polymer | 66 | 7677.6 | 1 | UniProt (O95149) Pfam (PF11538) | Homo sapiens (human) | RNA U transporter 1 |
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 50 | Chemie (HOH) |
Sequence modifications
A: 127 - 876 (UniProt: Q14974)
| PDB | External Database | Details |
|---|---|---|
| Ser 126 | - | cloning artifact |
| Gly 876 | Ala 876 | cloning artifact |
| Leu 877 | - | cloning artifact |
| Thr 878 | - | cloning artifact |
| Arg 879 | - | cloning artifact |
| Val 880 | - | cloning artifact |
| Asp 881 | - | cloning artifact |
| Ser 882 | - | cloning artifact |
| Ser 883 | - | cloning artifact |
| Gly 884 | - | cloning artifact |
| Arg 885 | - | cloning artifact |
| Ile 886 | - | cloning artifact |
| Val 887 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 92245.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 92437.2 |
