2QK9
Human RNase H catalytic domain mutant D210N in complex with 18-mer RNA/DNA hybrid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | 5'-R(*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3' | polymer | 18 | 5708.4 | 1 | |||
2 | C | 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*T)-3' | polymer | 18 | 5556.6 | 1 | |||
3 | A | Ribonuclease H1 | polymer | 154 | 17104.3 | 1 | UniProt (O60930) Pfam (PF00075) In PDB | Homo sapiens (human) | Hs-RNase HC; RNase H1; Ribonuclease H type II |
4 | B, C, A | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
5 | C | HEXANE-1,6-DIAMINE | non-polymer | 116.2 | 1 | Chemie (16D) | |||
6 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
7 | A | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
8 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
9 | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A: 136 - 286 (UniProt: O60930)
PDB | External Database | Details |
---|---|---|
Gly 133 | - | expression tag |
Ser 134 | - | expression tag |
His 135 | - | expression tag |
Asn 210 | Asp 210 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 28369.3 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1184.9 | |
All* | Total formula weight | 29554.2 |