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2QK9

Human RNase H catalytic domain mutant D210N in complex with 18-mer RNA/DNA hybrid

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0004523molecular_functionRNA-DNA hybrid ribonuclease activity
Functional Information from PDB Data
site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 B 1007
ChainResidue
BC8
BA9
C16D1004

site_idAC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 B 1008
ChainResidue
BG13
BA14
CDA25

site_idAC4
Number of Residues2
DetailsBINDING SITE FOR RESIDUE SO4 C 1009
ChainResidue
CDT30
CDC31

site_idAC5
Number of Residues6
DetailsBINDING SITE FOR RESIDUE NA A 9001
ChainResidue
AGLU186
AASN210
AHOH9037
BA9
BC10
AASP145

site_idAC6
Number of Residues13
DetailsBINDING SITE FOR RESIDUE FLC A 1001
ChainResidue
AVAL140
ATRP164
AHIS168
AGLY173
AGLN200
AILE202
AGLN283
AHOH9014
AHOH9018
AHOH9021
AHOH9038
AHOH9041
AHOH9045

site_idAC7
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 1005
ChainResidue
AARG157
AARG175
ASER284
AGLU285

site_idAC8
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 1006
ChainResidue
AHIS264
AHOH9054
BC10
BC11

site_idAC9
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 A 1010
ChainResidue
AARG153
CDG26
CDG27

site_idAD1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 A 1011
ChainResidue
AARG153
AARG154
AHOH9058

site_idBC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE 16D C 1004
ChainResidue
BA7
BSO41007
BHOH1027
CDT28
CDG29
CDT30
CHOH1033

site_idBC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE GOL A 1002
ChainResidue
AARG179
AARG184
AILE239
AASN240
AGLU242
AASP243

site_idBC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE GOL A 1003
ChainResidue
AHIS188
ACYS191
AGLU195

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00408
ChainResidueDetails
AASP145
AGLU186
AASN210
AASP274

226707

PDB entries from 2024-10-30

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