2QK4
Human glycinamide ribonucleotide synthetase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Trifunctional purine biosynthetic protein adenosine-3 | polymer | 452 | 48276.3 | 2 | UniProt (P22102) Pfam (PF02844) Pfam (PF01071) Pfam (PF02843) In PDB | Homo sapiens (human) | [Includes: Phosphoribosylamine-glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIRS) (Phosphoribosyl-aminoimidazole synthetase) (AIR synthase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (GART) (GAR transformylase) (5'-phosphoribosylglycinamide transformylase)] |
2 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
3 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
4 | A, B | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
5 | A, B | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
6 | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 430 (UniProt: P22102)
PDB | External Database | Details |
---|---|---|
Met -21 | - | cloning artifact |
His -20 | - | cloning artifact |
His -19 | - | cloning artifact |
His -18 | - | cloning artifact |
His -17 | - | cloning artifact |
His -16 | - | cloning artifact |
His -15 | - | cloning artifact |
Ser -14 | - | cloning artifact |
Ser -13 | - | cloning artifact |
Gly -12 | - | cloning artifact |
Val -11 | - | cloning artifact |
Asp -10 | - | cloning artifact |
Leu -9 | - | cloning artifact |
Gly -8 | - | cloning artifact |
Thr -7 | - | cloning artifact |
Glu -6 | - | cloning artifact |
Asn -5 | - | cloning artifact |
Leu -4 | - | cloning artifact |
Tyr -3 | - | cloning artifact |
Phe -2 | - | cloning artifact |
Gln -1 | - | cloning artifact |
Ser 0 | - | cloning artifact |
Ile 421 | Val 421 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 96552.7 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 1645.8 | |
All* | Total formula weight | 98198.4 |